Medical Complications Of Kidney Transplantation

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Etiopathogenesis Identification of the novel human herpes virus HHV-8 (Chang et al., 1994; Moore and Chang, 1995) has allowed higher understanding of the pathogenesis of KS. However, the presence of HHV-8 is not enough per se to trigger the development of KS. The improvement of KS requires the reactivation of HHV-8, which could be triggered by a compromised host immune response and/or the evasion of infected cells by the host NK cell-driven response (Sirianni et al., 2002).

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